In vivo bioluminescence imaging system at UCSF

Definition
An image acquisition instrument that is designed for non-invasive in vivo use, to detect bioluminescence, which is based on the expression of luciferase, the light-emitting enzyme of the firefly Photinus pyralis. After the administration of the substrate luciferin, an ATP- and O2-dependent photochemical reaction occurs, resulting in the release of photons by living cells containing luciferase. This photon emission can be detected by a cooled charge-coupled device (CCD) camera, minutes after the administration of the substrate.
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→ In vivo bioluminescence imaging system
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All Mission Bay Mt. Zion
Mission Bay, Mt. Zion

Cancer Center Preclinical Therapeutics Core

Helen Diller Family Comprehensive Cancer Center, Mission Bay, Mt. Zion
Contact: Rosa Navarro veronica.steri@ucsf.edu

  • Bioluminescent imaging
  • Xenogen IVIS 100 imaging
  • Xenogen IVIS SPECTRUM imaging