In vivo bioluminescence imaging system at UCSF

Definition
An image acquisition instrument that is designed for non-invasive in vivo use, to detect bioluminescence, which is based on the expression of luciferase, the light-emitting enzyme of the firefly Photinus pyralis. After the administration of the substrate luciferin, an ATP- and O2-dependent photochemical reaction occurs, resulting in the release of photons by living cells containing luciferase. This photon emission can be detected by a cooled charge-coupled device (CCD) camera, minutes after the administration of the substrate.
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Mission Bay, Mt. Zion

Cancer Center Preclinical Therapeutics Core

UCSF Helen Diller Family Comprehensive Cancer Center, Mission Bay, Mt. Zion
Contact: Byron Hann 415-476-0419 bhann@cc.ucsf.edu

  • Bioluminescent imaging
  • Xenogen IVIS 100 imaging
  • Xenogen IVIS SPECTRUM imaging
Mission Bay, Mt. Zion, Parnassus

Laboratory for Cell Analysis (Diller Comprehensive Cancer Center Cytometry Core)

UCSF Helen Diller Family Comprehensive Cancer Center, Mission Bay, Mt. Zion, Parnassus
Contact: Ben Braun 415-514-4176 braunb@peds.ucsf.edu

  • Xenogen IVIS Zeiss with color camera
Parnassus

Biological Imaging Development Center

Department of Pathology, Parnassus
Contact: Kaitlin Corbin 415-476-4550 kaitlin.corbin@ucsf.edu

  • Xenogen IVIS SPECTRUM Imager
SFGH, Parnassus, China Basin, Mt. Zion

Brain Tumor Research Center Pre-clinical Therapeutic Testing Core

Neurological Surgery, SFGH, Parnassus, China Basin, Mt. Zion
Contact: Tomoko Ozawa 415-476-9756 tomoko.ozawa@ucsf.edu

  • Xenogen